Israeli soldiers shot and killed 16 people waiting for humanitarian aid to be distributed in the Gaza Strip, according to Palestinian doctors at the Shifa Hospital in Gaza City on Saturday.
The 16 Palestinians were waiting near the northern Zikim border crossing for trucks carrying humanitarian aid.
A further 300 people were injured, the doctors said.
The Israeli military has not commented on the incident and the information could not initially be independently verified.
Gazans have been shot repeatedly while waiting for the distribution of humanitarian aid or near border crossings.
An Israeli and UN-backed rival aid group called Gaza Humanitarian Foundation (GHF) has been operating in the coastal strip in recent times, but there have been widespread Palestinian media reports of Israeli attacks on those waiting in line for help.
GHF distribution centres are also guarded by private US security firms.
Israel’s military has said in the past that soldiers shoot at suspects if they approach troops without permission or enter restricted areas.
The foundation has repeatedly denied the reports but according to the UN, hundreds of deaths have already occurred at GHF distribution stations since the end of May.
Israel introduced the new distribution mechanism, claiming it was to prevent the Hamas from diverting aid supplies.
Previously, the UN operated around 400 distribution stations for the approximately 2 million Palestinians in the region. These stations are now barely functioning, as Israel has almost entirely blocked their resupply.
International aid organizations describe the situation on Gaza as catastrophic.
As Israel allows only limited humanitarian aid into the sealed-off strip, most of the population is starving.
More than 100 people have already died of malnutrition, 80% of whom were children, according to the local health authority.
Israel denies that there is a famine in the Gaza Strip.
Israel blames UN organisations for the food shortage claiming they do not distribute the aid deliveries in the Gaza Strip. The UN says the Israeli military often does not provide safe transport routes within the coastal strip.
According to COGAT, the Israeli military authority responsible for approving and coordinating aid transports, 100 trucks with humanitarian aid entered the Gaza Strip on Friday. UN organizations distributed the goods, COGAT said.
But in recent weeks, the UN says only a few aid convoys have reached the area. For Gaza to receive adequate supplies, at least 500 trucks a day would be needed.